1,265 research outputs found

    PonyGE2: Grammatical Evolution in Python

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    Grammatical Evolution (GE) is a population-based evolutionary algorithm, where a formal grammar is used in the genotype to phenotype mapping process. PonyGE2 is an open source implementation of GE in Python, developed at UCD's Natural Computing Research and Applications group. It is intended as an advertisement and a starting-point for those new to GE, a reference for students and researchers, a rapid-prototyping medium for our own experiments, and a Python workout. As well as providing the characteristic genotype to phenotype mapping of GE, a search algorithm engine is also provided. A number of sample problems and tutorials on how to use and adapt PonyGE2 have been developed.Comment: 8 pages, 4 figures, submitted to the 2017 GECCO Workshop on Evolutionary Computation Software Systems (EvoSoft

    Coca and Conservation: Cultivation, Eradication, and Trafficking in the Amazon Borderlands

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    The cultivation and traffic of coca, Erythrolxylum coca, and coca derivatives remain understudied threats to the conservation of the Amazon rainforest. Currently the crop is transforming land use and livelihoods in the ecologically and culturally rich borderlands of Amazonian Peru. The isolated nature of this region characterized by indigenous populations (both settled and uncontacted), conservation units, resource concessions, and a lack of state presence provides fertile ground for the boom and bust cycle of coca production and facilitates the international transport of the product to neighboring Brazil. This paper explores the social and environmental impacts of coca production, eradication, and transport through an analysis of both spatial and ethnographic data on land use and livelihood strategies along the Ucayali and Purús Rivers. Results map out the regional distribution and recent history of commercial coca fields and transboundary transportation routes and identify threats to the conservation of indigenous landscapes and borderland forests

    OAIster on EBSCO Discovery Service, FirstSearch, and OAIster.worldcat.org

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    This review of OAIster investigated the utility of OAIster as a tool for library users to discover and access relevant information. Because the vision for OAIster is so large, one goal of this review was to describe OAIster based on reviewing search results. FirstSearch, OAIster.worldcat.org, and EBSCO Discovery Service interfaces were reviewed. Five searches were performed in each interface, and the material types and counts were recorded. Because OAIster is intended to link only to publicly accessible resources, links to resources were also tested. The review found large differences across interfaces in the number of results, classification of records into material types, and access to resources. Discovery tools do not always map OAIster metadata effectively, and public search engines do not seem to thoroughly index OAIster. Some OAIster records link to non-full–text or not publicly accessible resources. OAIster is a valuable tool for discovering resources in archives, special collections, and institutional repositories, but its place among Open Access search tools is still somewhat unclear

    Scleroderma and pulmonary hypertension

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    Reformulation initiative for partial replacement of saturated with unsaturated fats in dairy foods attenuates the increase in LDL cholesterol and improves flow-mediated dilatation compared with conventional dairy: the randomized, controlled REplacement of SaturatEd fat in dairy on Total cholesterol (RESET) study

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    Background Modifying dairy fat composition by increasing the MUFA content is a potential strategy to reduce dietary SFA intake for cardiovascular disease (CVD) prevention in the population. Objectives To determine the effects of consuming SFA-reduced, MUFA-enriched (modified) dairy products, compared with conventional dairy products (control), on the fasting cholesterol profile (primary outcome), endothelial function assessed by flow-mediated dilatation (FMD; key secondary outcome), and other cardiometabolic risk markers. Methods A double-blind, randomized, controlled crossover 12-wk intervention was conducted. Participants with a 1.5-fold higher (moderate) CVD risk than the population mean replaced habitual dairy products with study products (milk, cheese, and butter) to achieve a high-fat, high-dairy isoenergetic daily dietary exchange [38% of total energy intake (%TE) from fat: control (dietary target: 19%TE SFA; 11%TE MUFA) and modified (16%TE SFA; 14%TE MUFA) diet]. Results Fifty-four participants (57.4% men; mean ± SEM age: 52 ± 3 y; BMI: 25.8 ± 0.5 kg/m2) completed the study. The modified diet attenuated the rise in fasting LDL cholesterol observed with the control diet (0.03 ± 0.06 mmol/L and 0.19 ± 0.05 mmol/L, respectively; P = 0.03). Relative to baseline, the %FMD response increased after the modified diet (0.35% ± 0.15%), whereas a decrease was observed after the control diet (−0.51% ± 0.15%; P< 0.0001). In addition, fasting plasma nitrite concentrations increased after the modified diet, yet decreased after the control diet (0.02 ± 0.01 μmol/L and −0.03 ± 0.02 μmol/L, respectively; P = 0.01). Conclusions In adults at moderate CVD risk, consumption of a high-fat diet containing SFA-reduced, MUFA-enriched dairy products for 12 wk showed beneficial effects on fasting LDL cholesterol and endothelial function compared with conventional dairy products. Our findings indicate that fatty acid modification of dairy products may have potential as a public health strategy aimed at CVD risk reduction. This trial was registered at clinicaltrials.gov as NCT02089035
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